Ksenia Krupina, PhD is an Assistant Professor in the Department of Biochemistry and Molecular Biology at the University of Iowa. Her research focuses on mechanisms of genome instability in cancer, with particular emphasis on chromothripsis, micronuclei, and extrachromosomal DNA (ecDNA).

Dr. Krupina received her PhD in Biology from the University of Strasbourg, where she studied regulation of mitotic chromosome segregation and nuclear dynamics. She completed postdoctoral training in the laboratory of Don W. Cleveland at the University of California San Diego, where she discovered the cytoplasmic nuclease N4BP2 as a key trigger of chromosome shattering following nuclear envelope rupture. This work provided a molecular mechanism for chromothripsis and was published in Science.

Throughout her research career, Dr. Krupina has combined cell biology, biochemistry, advanced microscopy, and genomics to study chromosome segregation, nuclear integrity, and genome rearrangements. Her work has been recognized by multiple fellowships and awards, and she has authored publications in Science, Cell, Nature Reviews Genetics, Developmental Cell and others.